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	Provedor de dados BJMBR (1) Autor Lunardi,C.N. (1) Rotta,J.C.G. (1) Tedesco,A.C. (1) Palavra-chave Liposomes (1) Nitric oxide (1) Photodynamic therapy (1) S-nitrosothiols (1) Zinc phthalocyanine (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Nitric oxide release from the S-nitrosothiol zinc phthalocyanine complex by flash photolysis BJMBR Rotta,J.C.G.; Lunardi,C.N.; Tedesco,A.C.. The photogeneration of nitric oxide (NO) using laser flash photolysis was investigated for S-nitroso-glutathione (GSNO) and S-nitroso-N-acetylcysteine (NacySNO) at pH 6.4 (PBS/HCl) and 7.4 (PBS). Irradiation of S-nitrosothiol with light (lambda = 355 nm followed by absorption spectroscopy) resulted in the homolytic decomposition of NacySNO and GSNO to generate radicals (GS· and NacyS·) and NO. The release of NO from donor compounds measured with an ISO-Nometer apparatus was larger at pH 7.4 than pH 6.4. NacySNO was also incorporated into dipalmitoyl-phosphatidylcholine liposomes in the presence and absence of zinc phthalocyanine (ZnPC), a well-known photosensitizer useful for photodynamic therapy. Liposomes are usually used as carriers for hydrophobic... Tipo: Info:eu-repo/semantics/article Palavras-chave: S-nitrosothiols; Nitric oxide; Zinc phthalocyanine; Liposomes; Photodynamic therapy. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000500005 Registros recuperados: 1 Primeira ... 1 ... Última

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